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L.HartD

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A larger randomized, placebo-controlled intervention trial (the SELECT study) in more than 35,000 middle-aged and selenium-replete men, randomized to receive selenium (in the form of selenomethionine, 200 g/day) and/or vitamin E supplementation, was halted because of concerns regarding an increased risk of type 2 diabetes mellitus with selenium and increased risk of prostate cancer with vitamin E (84, 85)

Effective reduction of fat tissue: Increased GH levels support metabolism and fat burning, leading to improved body composition

Many also lack proper placebo controls, which could mean some benefits come from people feeling hopeful about their treatment rather than the glutathione itself